Projects
Optical binding of nanoparticles outside the photon beam: creation of primeval optical matter KU Leuven
Microstructure development in multiphasic polymeric materials containing functional nanoparticles KU Leuven
mRNA Lipid nanoparticles co-loaded with alpha-Galactosylceramide as a universal influenza vaccine platform Ghent University
A universal influenza vaccine that in all population groups can provide long-term protection against different influenza strains, including new “pandemic” viruses, is most needed. In this project, we propose a novel vaccine platform, termed Galsomes, that is composed of lipid nanoparticles that co-deliver glycolipid antigens and mRNA encoding viral proteins to antigen presenting cells (APCs). Previous research learned us that activating ...
Lignin valorization into innovative hydroxylated aromatics through a one-pot catalytic process using supported bimetallic nanoparticles boosted by the development of 2D liquid chromatography Ghent University
This project aims to valorise lignin, a renewable biopolymer from woody plants, by producing reactive bio-aromatic monomers and oligomers with a high functionality through a one-pot simultaneous reductive depolymerisation and demethylation using supported bimetallic nanoparticles. Additionally, a novel method for two dimensional liquid chromatography will be developed and the effect of genetic modification of the lignin feed will be ...
Process Intensification in the Reactive Crystallization of Micro- and Nanoparticles KU Leuven
Study of the ultrasound effects on the micro- and nanoparticle synthesis of zeolites at lab scale. For a broad range of temperatures (50-150 °C) and pressures (1-10 bar) US frequency and power are studied for: 1) efficient mixing prior/during crystallization of micro- and nanoparticles, and for 2) de-agglomeration of the crystal aggregates. Micromixing studies are undertaken, as well as the evaluation of meta-stable zone width, induction time ...
Improved intracellular delivery of upconversion nanoparticles by laser-induced vapor nanobubbles for multimodal bio-imaging applications Ghent University
Vapor nanobubble induced membrane poration will be explored as novel method for efficient delivery of upconversion nanoparticles into the cytosol of living cells. Benefits for in vivo cell tracking will be demonstrated over standard endocytic nanoparticle uptake, including improved labeling uniformity, high-throughput cell labeling, reduced toxicity, improved long term visibility and better signal quantification.
In situ synthesis and anchoring of gold and titania nanoparticles on metal organic frameworks Ghent University
In this project water stable MOFs will be synthesized. In a second step the MOFs will be applied as host matrixes for the anchoring of gold and titania nanoparticles which will be synthesized in situ in the MOF framework. The resulting NP@MOF materials will be evaluated as catatalysts in the epoxidation of different olefins and as a photocatalyst.
Design and Synthesis of Multifunctional PPV-Based Nanoparticles for Multiple Sclerosis Research Hasselt University
removal of micropollutants from water using a combination of electrochemical sorption/desorption and biogenic nanoparticles. Ghent University
in this research, a technology will be developed for the effective treatment of water containing micropollutants. This technology will consist of a combination of a preconcentration step by electrochemical sorption/desorption and a degradation using biogenic nanoparticles as catalysts. The activity of the nanoparticles will be maximized bij an in-dept study of their structure and their structure-activity relationship.