Understanding the structure, function and mechanism of Synaptojanin1 in the context of neurological disease Vrije Universiteit Brussel
important cellular processes, including cell signaling, exo- and
endocytosis, and synaptic vesicle trafficking. Consequently, the PIP
levels in the cell are regulated by a variety of kinases and
phosphatases. Synaptojanin1 (Synj1) is a pre-synaptic enzyme,
containing two catalytic PIP phosphatase domains: the so-called
SAC1 and 5-PPase ...