Projects
MULTISCALE - The UHasselt MultiScale Optical Imaging Core: Infrastructure for nano- to centimeter length scale microscopy and analysis of 'big' 4D datasets Hasselt University
TRPV4 as a key driver of branch motility and somatic migration of microglial cells Hasselt University
Limbic and paralimbic cortex in primary progressive aphasia: a multi-level analysis KU Leuven
Primary progressive aphasia (PPA) is a rare neurodegenerative syndrome characterized by a relatively isolated language impairment. Often, PPA patients exhibit behavioral and social changes beyond the language symptoms as well. The clinical manifestation of symptoms depends on the underlying anatomical regions and neuronal cell populations affected. Currently, it remains a fundamental question why certain areas of the brain are vulnerable to ...
Representation of concepts in health & neurodegenerative disease: a subject-specific multivariate approach based on representational similarity analysis using fMRI and MEG KU Leuven
During this project, we want to investigate how concrete entities (animals, objects) are represented in the human brain. We will examine healthy controls and patients suffering from neurodegenerative disease. In our previous work, we discovered that when the meaning of words is more alike, the brain response patterns in the left temporal lobe are also more alike. We performed these studies on large groups of healthy young volunteers. Now, we ...
The contribution of the medial temporal system in humans to semantic processing of words and pictures. KU Leuven
The brain contains several memory systems. Episodic memory deals with episodes in a particular space and time context and is typically associated with structures deep in the temporal lobe (the medial-temporal lobe system). An episodic memory deficit is commonly seen in Alzheimer's disease (AD). Semantic memory refers to our knowledge of the world, the meaning of words and pictures and associations between concepts. Patients with semantic ...
Spatial-attentional priorities as an emerging property of dynamic brain networks and robustness to focal damage. KU Leuven
The external environment and our inner mental state consist of a large number of discrete elements, too many to process in detail at the same time and most of them irrelevant to our goals or interests. For that reason, when we are awake, we continuously select input from the external environment or from our inner mental states. This selection process happens spontaneously and determines, for instance, which stimuli we are aware of and which ...
Using transcranial magnetic stimulation induced interference to explore functional-anatomical network models of visuospatial and motor attention. KU Leuven
Fundamental scientific research of the structural and functional neurological characteristics of neurogenic stuttering. KU Leuven
Uncovering short- and long-term circuit mechanisms of locomotor rehabilitation after spinal cord injury. KU Leuven
Severe spinal injuries disrupt communication between the brain and circuits below the lesion. Therapeutic approaches aim for functional recovery by facilitating axonal growth, removing growth barriers, or replacing lost cells. However, all approaches face a common challenge: the spinal cord below the injury must adapt to function with limited brain input. Rehabilitative training facilitates locomotor recovery by “teaching” the spinal cord to ...