Projects
Integrated Personalized & Precision Oncology Network (IPPON). University of Antwerp
Research in the field of oncology. University of Antwerp
Exploratory research into the employability of indirect calorimetry in function of nutritional advice in oncology patients in active treatment. VIVES
Real-time qPCR platform enhancing research activities within the Laboratory of Experimental Oncology and the Laboratory of Experimental Radiotherapy KU Leuven
Approaching personalized oncology with DNA methylation inference and computational epigenomics KU Leuven
Epigenomic profiles have unspent capacity for diagnostic and prognostic oncological applications. I hypothesize that computational methods to understand the key dimensions shaping tumor epigenomes – cellular heterogeneity, genome-epigenome interplay, cancer cell-of-origin and non-genetic evolution – will provide crucial personalized insights into tumor microenvironment, expression of somatic mutations, cancer emergence and progression. ...
PROMICE: Advancing Precision Oncology via Methylome Inference and Computational Epigenomics KU Leuven
Research in the field of oncology. University of Antwerp
Building a next-generation precision oncology platform for childhood cancer Ghent University
Improved patient tailored, more potent and durable treatment of childhood cancer is an urgent medical need. Childhood cancers are often still treated by a ‘one-fits-all’ approach, given the limited available entry points for targeted therapy. Molecular dissection of pediatric cancers, using multiple layers of information (so-called ‘omics’) up to the single cell level, is nowadays yielding fundamental insights into novel putative targets and ...