Complex personalized organ-on-chip models to study the dynamics of cystic fibrosis pathophysiology KU Leuven
Biomedical research largely depends on simplified in vitro systems
(e.g. immortalized cell lines) or in vivo animal models. Unfortunately,
these systems are not sufficiently predictive of human
pathophysiology, hampering the successful translation of
experimental results to human medicine. 2D/3D patient-derived cell
cultures, including organoids, are gaining momentum as more
reliable disease models compatible ...