Projects
Protective potential of obesity against critical illness induced muscle wasting KU Leuven
Kritieke ziekte is elke acute medische conditie waarvoor de patiënt intensieve medische ondersteuning nodig heeft van vitale organen om te kunnen overleven. Ondanks vooruitgang in de intensieve geneeskunde, heeft ongeveer 30% van de kritiek zieke patïenten langdurig nood aan intensieve zorgen. Deze verlengde vorm van kirtieke ziekte gaat samen met hypercatabolisme, spierverlies en spierzwakte, wat ook kan zorgen voor verlengde nood aan ...
Preventing obesity through Biologically and bEhaviorally Tailored inTERventions for you Ghent University
BETTER4U aims to unveil the interplay between obesity biological and lifestyle determinants and close the current gap between
research and effective personalized interventions for obesity prevention. Building on previous key projects and biobanks, the project
will focus on the hitherto neglected impact of the polygenic background of weight gain on the effectiveness of lifestyle interventions
for weight management in people ...
Lipid metabolism in obesity and aging-induced cancer metastasis KU Leuven
Known risk factors for breast cancer metastasis and poorer prognosis at the metastatic stage are obesity1 and age2, which both result in increased body fat mass3. We have found that inhibiting CPT1A, which is important for fat processing, impairs metastasis formation in obese mice. We aim to understand: 1. How fat processing supports metastasis formation. 2. To which extent targeting fat processing will impair already established metastases ...
Unravelling chronic postsurgical pain after total knee replacement: what is the role of altered central pain processing and metabolic disorders such as obesity and diabetes? University of Antwerp
Stratification of Obese Phenotypes to Optimize Future Obesity Therapy KU Leuven
Obesity is a global pandemic, currently affecting around 150 million people in Europe and 650 million people worldwide. Obesity complications are common, in fact obesity is associated with some 200 complications, but we cannot yet predict who will develop the complications of obesitybe affected. Moreover, there are no predictors for who will respond to obesity treatments. SOPHIA will therefore identify and characterise clinically-meaningful ...
The role of adipose tissue hypoxia in obesity and obstructive sleep apnea. University of Antwerp
Characterization of coding and non-coding RNA transcripts and of epigenetic markers in obesity. KU Leuven
This project investigates the role and the properties of coding and non-coding RNA transcripts and also of epigenetic markers in obesity and their role in the weight loss induced by gastric bypass surgery.