Projects
Motion compensation for PET in TOF-PET/CT and TOF-PET/MR brain imaging KU Leuven
Prototyping and validation of a system for unrestrained awake brain PET imaging of small laboratory animals. University of Antwerp
PET imaging of free running rats with a high resolution human scanner for simultaneous behavioral neuroscience and imaging University of Antwerp
BEyOND: Brain pEt to Overcome Neurodegenerative Diseases. KU Leuven
BEyOND trains ESR fellows in innovative approaches to develop quantitative brain PET imaging for better patient care and accelerated drug development for neurodegenerative diseases. Brain disorders are a major public health problem in Europe, and pharmaceutical drugs are the predominant therapeutic approach. In order to manage the constantly increasing healthcare and drug development costs, there is an urgent need for next-generation ...
Activity-based probes for PET imaging of protease activity. University of Antwerp
Remote controlled miniaturized radiotracer injection device for dynamic PET imaging in free running small animals. University of Antwerp
PET imaging of the mGluR5 receptor in addiction: its role in deficient corticostriatal control and glutamatergic modulation of dopaminergic neurotransmission KU Leuven
Addiction is a complex brain disorder, leading to a compulsive obsession to use a substance despite serious detrimental consequences. Apart from a dysfunctional reward system, reduced inhibitory corticostriatal control in drug-seeking and drug-taking1 and vulnerability to addiction2 has been emphasized. Genetic, developmental, and environmental factors are major contributors to addiction risk, but the neurobiological processes that underlie ...
Development of novel imaging tracers for proteolitic remodelling of the brain extracellular matrix following traumatic brain injury University of Antwerp
Rigid Motion Correction for Positron Emission Tomography Brain Imaging KU Leuven
During a positron emission tomography (PET) scan the subject is required to be completely stationary for the duration of the scan. Any motion of the subject will translate into motion blur in the final reconstructed image and may reduce the diagnostic value of the image. Motion during a PET scan can be classified into two main categories: non-rigid and rigid motion. Non-rigid motion deforms the subject and is primarily caused by motion in the ...