Projects
Motion compensation for PET in TOF-PET/CT and TOF-PET/MR brain imaging KU Leuven
Data-driven brain and heart PET imaging of awake rodents. University of Antwerp
PET imaging of the mGluR5 receptor in addiction: its role in deficient corticostriatal control and glutamatergic modulation of dopaminergic neurotransmission KU Leuven
Addiction is a complex brain disorder, leading to a compulsive obsession to use a substance despite serious detrimental consequences. Apart from a dysfunctional reward system, reduced inhibitory corticostriatal control in drug-seeking and drug-taking1 and vulnerability to addiction2 has been emphasized. Genetic, developmental, and environmental factors are major contributors to addiction risk, but the neurobiological processes that underlie ...
Activity-based probes for PET imaging of protease activity. University of Antwerp
Development of novel cell death PET imaging probes for early treatment response assessment. University of Antwerp
Development of a caspase-3 selective activity-based probe for PET imaging of apoptosis University of Antwerp
Remote controlled miniaturized radiotracer injection device for dynamic PET imaging in free running small animals. University of Antwerp
Deep Learning Enhanced Parametric 4D Total Body PET Imaging Ghent University
TB-PET provides tools to image dynamic radiopharmaceutical distribution in the whole body, simultaneously capturing the uptake in different organs. We aim to investigate the potential of DL for enhancing image quality of parametric maps generated from such 4D (3D + time) TB-PET studies. The goal is to apply DL for direct parametric map estimation in clinical and preclinical settings.