Projects

Clinical validation ('check of medication appropriateness') gains importance in Belgium for the organisation of clinical pharmacy. Patient records are screened electronically for potential inappropriate prescriptions (medication errors), which are then checked by a clinical pharmacist. When a medication error is noticed by the clinical pharmacist, advice is given to the physician. This type of clinical pharmacy makes it possible to deliver ...

High drop-out rates at university level indicate that students are not able to find what they expected at the university. It is a problem in many European countries. Reports from European Commission and universities, mentioned that relating the courses in their programs to e.g. the disciplinary future selves (DFSs) of the students is one of the solutions by enhancing students’ learning and affective states (e.g. motivation and interest). The ...

Histone posttranslational modifications have long been recognized to be crucial epigenetic regulators that mediate health, disease and survival. My endpoint goal will be to incorporate the latest in data acquisition and analysis into the toxicoepigenetic mass spectrometry-based assay that is currently under development at the Lab of Pharmaceutical Biotechnology, in order to improve the reliability of the assay report.

The production of proteins by using genetically modified organisms has become a multibillion-euro industry thanks to the multitude of applications. Specifically in the pharmaceutical industry, proteins are being produced in this manner to obtain a reliable and cost-efficient production process. However, the optimisation of these complex production processes is not yet taking advantage of the state-of-theart computational techniques that are ...

Medicine and vaccine filling lines in isolator systems are becoming increasingly important to the pharmaceutical industry. Currently, human interventions in such isolators are performed by means of gloves in glove ports. Consequently, the barrier between an operator and the sterile process is only a glove, which cannot provide full guarantee of sterile integrity. In addition, any intervention by an operator puts the moving parts of a filling ...

The ExaScience Life project enables Intel, Janssen, Imec and the universities to learn how HPC should be applied to life sciences problems. The biostatistics and genetics applications will be used as a concrete example of such applications. As described in the following work units, this involves research in a wide range of scientific fields, which is necessary given the different areas of technical expertise required to achieve the bridging ...

In 1999, the US Institute of Medicine released a report titled “To Err is Human: building a Safer Health System”, which addressed the potential impact of medical errors on health care and patient morbidity and mortality. According to this report, in 1993 alone, about 7000 deaths in the US could be directly attributed to medication errors. As a result of these unsettling findings, during the last two decades, much effort has been put into ...