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Towards personalised medicine in psoriasis Ghent University
Psoriasis is a chronic inflammatory disease of the skin with a strong genetic basis. In the past decade, great leaps have been made in understanding the molecular basis of psoriasis, and with this new knowledge, better treatment options were introduced for those with recalcitrant psoriasis. However, despite the plethora of new treatment options and biologics to treat the most difficult cases of psoriasis, dermatologists are still confronted with ...
Personalised medicine in de forensische psychiatrie University of Antwerp
achtergrond Personalised medicine is de belofte van diagnostisch-voorspellende stratificatie op basis van een biologische, cognitieve, demografische, psychopathologische of een anders omschreven test. Het doel van de forensische psychiatrie is niet alleen de zorg en de behandeling van delinquenten met een psychiatrische stoornis, maar ook risicotaxatie en -management. doel De risicotaxatie in de forensische psychiatrie als een nomothetische ...
Personalised medicine in Crohn's disease KU Leuven
Similar to many immune-mediated diseases, Crohn's disease follows a relapsing-remitting pattern, with a variable disease course and heterogeneous clinical outcomes. Frequency of flare-ups, development of complications, and response to treatment collectively determine the effect on a patient's quality of life, which can vary from minimal disruption to profound disability or death. Despite recent advances in the understanding of complex disease ...
Personalised medicine University of Antwerp
Personalised medicine wordt beschouwd als één van de grote beloftes voor de geneeskunde (FIGUUR 1; Nationale Wetenschapsagenda 2016). De gedachte is dat geneeskundige interventies (preventie, cure en care) niet effectief zijn bij een kwart tot twee derde van de patiënten. Dit geldt ook voor behandelingen die als effectief te boek staan omdat ze in grote klinische trials, gemiddeld genomen, effect hebben.
Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine Flanders Institute for Biotechnology KU Leuven
A Proposal for a Study on Treatment Selection and Lifestyle Recommendations in Chronic Inflammatory Diseases: A Danish Multidisciplinary Collaboration on Prognostic Factors and Personalised Medicine Flanders Institute for Biotechnology KU Leuven
Harnessing System Models of Cell Death Signalling for Cytotoxic Chemotherapy: Towards Personalised Medicine Approaches? KU Leuven
Most cytotoxic chemotherapeutics are believed to kill cancer cells by inducing apoptosis. Understanding the factors that contribute to impairment of apoptosis in cancer cells is therefore critical for the development of novel therapies that circumvent the widespread chemo-resistance. Apoptosis, however, is a complex and tightly controlled process that can be induced by different classes of chemotherapeutics targeting different signalling nodes ...
Predicting outcome of inflammatory bowel diseases, a multi-omics approach: creating opportunities for personalised medicine KU Leuven
The imminent introduction of new therapies for both Crohn's disease (CD) and ulcerative colitis (UC), will have a huge impact on our clinical practice in the coming years. However, it is anticipated that clinical response to each of these agents will vary significantly between individuals. Furthermore, these new therapies are expensive and long-term use may be associated with adverse events. Another important drawback for treatment with ...