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Consumer perceptions of electrocardiography-enabled smartwatches in health management Ghent University

Martijn Clarysse, Lieven De Marez, Koen Ponnet
Smartwatches with electrocardiography (ECG) functionality, capable of detecting cardiac arrhythmias, are promoted as accessible tools for early detection and prevention in cardiovascular healthcare. Despite their popularity, these devices have not been conclusively linked to improved long-term health outcomes – such as reduced stroke risk – in large scale randomized controlled trials. This raises the question whether popularity is driven by ...

Inflammatory markers and self-regulation improvements in children and adolescents with obesity during inpatient treatment University of Antwerp Ghent University

Eline Vermeiren, Annelies Van Eyck, Luc Bruyndonckx, Benedicte De Winter, Kim Van Hoorenbeeck, Stijn Verhulst
Obesity, self-regulation, and inflammation interact through complex physiological and psychological pathways. Inflammation may not only impair self-regulation in youth with obesity but could also interfere with their ability to develop these skills, thereby hindering positive changes in unhealthy obesity-related behaviors. Given the limited research on this topic in youth with obesity, the current study explored the associations between ...

Educating women to prevent and treat low back and pelvic girdle pain during and after pregnancy: a systematized narrative review KU Leuven

Liesbet De Baets
PURPOSE: This review evaluated the effectiveness of patient education and information on low back pain (LBP) and pelvic girdle pain (PGP) in pregnant and postpartum women and evaluated their alignment with modern pain education principles rooted in the biopsychosocial model. METHOD: A systematized narrative review was performed, including a systematic search of three databases and reference screening from relevant systematic reviews. The ...

Treating complex PTSD with Schema Therapy, ImRs and EMDR: a review and case study. KU Leuven

Laurence Claes
Introduction: Complex PTSD (CPTSD) often results from prolonged trauma, such as childhood abuse or domestic violence. Cognitive Behavioral Therapy (CBT) and Eye Movement Desensitization and Reprocessing (EMDR) are recommended for treating PTSD. However, their limited effectiveness for CPTSD highlights the need for alternatives such as Schema Therapy (ST) and Imagery Rescripting. This case study evaluates the effectiveness of a combined therapy ...

Unravelling the miscellaneous effects of exercise interventions on activities of daily living in frail older adults Vrije Universiteit Brussel University of Antwerp

Emma De Keyser, Jade Tambeur, Elke De Smedt, Dimitri Vrancken, Wim Peersman, Lieven Annemans, Siddhartha Lieten, Dominique Van de Velde, Patricia De Vriendt, David Beckwée, et al.

INTRODUCTION: Frailty in older adults impairs Activities of Daily Living (ADL). While exercise interventions improve factors like muscle strength and physical function, their direct impact on ADL ability is inconsistent. This review aims to assess the effectiveness of exercise on ADL ability, identify the most beneficial interventions, and explore mediators.

METHOD: A systematic search in five databases included randomized controlled ...

Catheter Ablation vs. Anti-Arrhythmic Drug Therapy for Ventricular Tachycardia in Ischemic Heart Disease: A Meta-Analysis of Randomized Controlled Trials. KU Leuven

Bert Vandenberk
BACKGROUND: Ventricular tachycardia (VT) in ischemic heart disease (IHD) requires complex management strategies including catheter ablation (CA) and anti-arrhythmic drugs (AADs). AIM OF THE STUDY: To compare efficacy and safety of CA versus AADs in patients with IHD and VT. METHODS: We performed a meta-analysis of randomized controlled trials (RCTs) enrolling patients with IHD and ICD randomized to CA or AADs. Primary outcome was appropriate ICD ...

A European multi-center, randomized controlled trial of Pirfenidone in bronchiolitis obliterans syndrome after bilateral lung transplantation. KU Leuven

Robin Vos
BACKGROUND: Chronic Lung Allograft Dysfunction (CLAD) is a major obstacle to improving outcomes after lung transplantation. Bronchiolitis Obliterans Syndrome (BOS), characterized by progressive decline in FEV1 due to fibrotic scarring of the small airways, accounts for most CLAD cases. Pirfenidone, an antifibrotic agent used for idiopathic pulmonary fibrosis (IPF), was assessed for treating progressive BOS. METHODS: An investigator initiated, ...

Effects of Transcranial Stimulation on Resistance Exercise in Mentally Fatigued Subjects Vrije Universiteit Brussel

Dalton de Lima-Júnior, Bart Roelands, Daniel Boullosa, Maria Elisa Caputo Ferreira, Leonardo de Sousa Fortes

The objective was to analyze the effect of Anodic transcranial direct current stimulation (a-tDCS) over the the primary motor cortex (M1) on resistance exercise in mentally fatigued individuals. Thirty-five participants performed a Stroop task (ST) to induce mental fatigue (MF) until they reached 50 mm on the visual analogue scale under three different conditions in a randomized, double-blind, crossover experimental trial. The participants ...

Efficacy of once-daily, high-dose, oral insulin immunotherapy in children genetically at risk for type 1 diabetes (POInT): a European, randomised, placebo-controlled, primary prevention trial. KU Leuven

Kristina Casteels, An Jacobs
BACKGROUND: Type 1 diabetes begins with autoimmunity against pancreatic islet antigens, including insulin. The aim of the Primary Oral Insulin Trial (POInT) was to evaluate the efficacy and safety of daily high-dose oral insulin to prevent the development of islet autoantibodies and diabetes. METHODS: In this randomised, controlled, primary prevention trial, genetic screening in seven obstetric and paediatric clinics in Germany, Poland, Sweden, ...