Glucose-induced activation of protein phosphatase PP2A and control of hyperactive glycolysis and Ras activity KU Leuven
This project investigates a fundamental property of cells: how energy production is coupled to cellular multiplication. Cancer cells multiply in an uncontrolled way and they also have an aberrant energy production. They mainly use fermentation, the converson of sugar into lactic acid, for energy provision, rather than respiration. It remains unclear whether this is just a consequence or may play a role in causing or maintaining the cancerous ...