Tackling major pitfalls in lung transplantation KU Leuven
Lung transplantation (LTx) is still hampered by two major problems namely organ shortage, which prolongs waiting times and waiting list mortality, and chronic rejection (CR), the most important cause of late morbidity and mortality after LTx. CR is clinically marked by a decline in forced expiratory volume in one second (FEV1) and histologically by obliterative bronchiolitis (OB) lesions. In our research we focused on both these problems. ...