Neutrophil Extracellular Traps, von Willebrand factor and Extracellular DNA as mediators of Ischemic Stroke Pathogenesis KU Leuven
Ischemic stroke, caused by an occluding thrombus which hinders cerebral blood flow, is still one of the leading causes of death and sustained disability worldwide. Nowadays, ischemic stroke management relies on the rapid removal of the occluding thrombus, thereby allowing reperfusion of the ischemic territory. Pharmacological thrombolysis or mechanical thrombectomy, which are currently the only approved strategies to recanalize the occluded ...