Development of a novel method for single-cell whole-genome amplification to study cancer heterogeneity. KU Leuven
All the cells in a human body have arisen from one single cell, the zygote. Throughout development cells divide, make fate decisions, and transition between different cell types and cell states. Every cell division the genetic code is copied and passed on to the daughter cells. While this is under tight control, mistakes do occur. In most cases these mutations have no effect, but they can have severe consequences as is exemplified by the ...