SPEED-XM: SPectral Evaluation and Enhanced Deconvolution by eXtensive (Statistical) Modelling. Hasselt University
Centre for Statistics, Janssen Pharmaceutica NV (Belgium)
A number of key-operations in pharmaceutical development, rely on a correct and timely evaluation of spectral data: e.g, liquid chromatography- mass spectrometry (LC-MS) and solid state Nuclear Magnetic Resonance spectroscopy (ssNMR) are used for compound characterization and MS in a gas-phase setting is used to monitor the headspace of a chemical reactor during the production process of active pharmaceutical ingredients. Nowadays, high amounts ...