Projects
Nature-based coastal defense systems on waves-currents-seagrass interaction: interdisciplinary research on coastal and ecology engineering and marine biology Ghent University
Nature-based solutions that provide sustainable coastal protection using low environmental impact solutions are significant in the adaptation process towards global climate change. One opportunity of sustainable protection is offered by aquatic vegetation(seagrass, salt marshes, and mangroves) in the coastal zone, which is of high ecological value and provides natural coastal protection through attenuating waves, baffling currents and ...
Coastal defense systems based on the ‘Building with Nature’ principles: interdisciplinary project on coastal and ecology engineering and marine biology. Ghent University
Salt marsh and seagrass meadow ecosystems with high ecological and economical values play an important role in dissipating energy from waves and currents. In this research we develop a pioneering 3D numerical and analytical model validated using experiments from the new state-of-the-art wave &
current tank and seawater flume in GreenBridge, to achieve new insights in the waves-currentvegetation interaction.
Interlocking synthetic biology, systems biology and artificial intelligence to develop a more efficient metabolic engineering workflow: a highly efficient biotechnological production platform for monoclonal chitooligosaccharides. Ghent University
Today, synthetic biology (SynBio) and systems biology (SysBio) are developing at an unprecedented pace into major drivers of industrial biotechnology. Despite these recent advances, the transformation of wild type organisms into highly efficient microbial cell factories (MCFs) remains a truly daunting task due to the enormous complexity of microbial cells. Typically, to steer the strain engineering process a “Design-Build-Test-Learn” (DBTL) ...
Exploiting MELanoma disease comPLEXity to address European research training needs in translational cancer systems biology and cancer systems medicine. KU Leuven
Novel treatment options and associated personalised, patient-tailored therapies need to be explored and developed for highly heterogeneous and chemotherapy resistant cancers, such as malignant melanoma. This can only be achieved by industry-academia collaborations in newly emerging, innovative research disciplines such as translational cancer systems biology and systems medicine. These disciplines and the associated European training needs ...
SRP (Groeiers): Applied physics and systems biology. Towards a cross-disciplinary complex systems center @ VUB Vrije Universiteit Brussel
A systems biology approach for the ethylene synthesis during climactericripening of tomato fruit. KU Leuven
international trade. Color, taste, aroma, firmness are all decisive quality attributes that determine the purchasing behavior of cusumers and wholesalers. Overall fruit quality is highly dependent on the climacteric ripening process, which is ...
Bioframe, a bioinformatics framework for top down systems biology Ghent University
Systems biology can be defined as the study of biological systems as complex systems arising from interactions between its multiple components. The bioframe project aims at the design of an algorithmic platform for the integration of coupled expression or interaction datasets, pragmatic and useful for the biologist, highly integrated and flexible.
Syn/SysBio4COS: Combining synthetic and systems biology to unlock the potential of the hexosamine biosynthesis pathway for chitooligosaccharide production Ghent University
Turning microorganisms into highly efficient microbial cell factories (MCFs) is a daunting process due to the enormous cellular complexity, i.e., the vast metabolic network superimposed by a multilevel regulatory layer and the fragmentary knowledge thereof. Typically, to steer the strain engineering process a “Design-Build-Test-Learn” (DBTL) cycle is iteratively run. In this project, to move more successfully through this cycle and, hence, ...
Systems biology of Lysine acetylation in phage infection KU Leuven
Our modern-day molecular biology is founded on research centering bacterial viruses or bacteriophages. This research led to crucial insights in fundamental microbiology and resulted in the most commonly used biotechnological tools in research and industry. During phage infection phages 'hijack' the bacterial metabolism in efficient and diverse manners such as cell wall modification and changes in replication, transcription and translation. ...