Development and validation of a peripheral blood mRNA assay for the assessment of antibody-mediated kidney allograft rejection: A multicentre, prospective study KU Leuven
To monitor renal graft rejection, we currently rely on archaic tools, with serum creatinine and invasive renal graft biopsies. These strategies offer only late detection of graft damage, with potentially irreversible damage. Therefore, there is an unmet need for novel, preferably noninvasive markers to detect alloimmune damage earlier. We developed and validated a novel peripheral blood mRNA biomarker for antibody-mediated rejection, in a ...