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Cell viability and proliferation capability of long-term human dental pulp stem cell cultures Ghent University
BACKGROUND AIMS: Evaluation of cell viability is one of the most important steps of the quality control process for therapeutic use of cells. The aim of this study was to evaluate the long-term cell viability profile of human dental pulp stem cell (hDPSC) subcultures (beyond 10 passages) to determine which of these passages are suitable for clinical use and to identify the cell death processes that may occur in the last passages. METHODS: Four ...
Exposure to the proton scavenger glycine under alkaline conditions induces Escherichia coli viability loss Ghent University
Luminescent multiplex viability assay for Trypanosoma brucei gambiense Institute of Tropical Medicine
BACKGROUND: New compounds for the treatment of human African trypanosomiasis (HAT) are urgently required. Trypanosoma brucei (T.b.) gambiense is the leading cause of HAT, yet T.b. gambiense is often not the prime target organism in drug discovery. This may be attributed to the difficulties in handling this subspecies and the lack of an efficient viability assay to monitor drug efficacy. METHODS: In this study, a T.b. gambiense strain, recently ...
In vitro evaluation of viability, integrity and inflammation in genital epithelia upon exposure to pharmaceutical excipients and candidate microbicides Institute of Tropical Medicine
Microbicides are a promising approach for the prevention of HIV-1 transmission. Unfortunately, various candidates failed in clinical trials. In some cases, the candidate microbicide even resulted in enhanced virus transmission. Therefore, there is an urgent need to develop more predictive preclinical strategies to anticipate the in vivo efficiency/toxicity rate, including in vitro assays that evaluate effects on epithelial integrity and ...
Viability of Möbius topologies in [26] and [28] hexaphyrins Vrije Universiteit Brussel
Viability of Möbius topologies in [26] and [28] hexaphyrins
The financial viability of the fitness industry in Belgium Vrije Universiteit Brussel
Purpose: This study aims to analyze whether the fitness industry in Belgium is financially viable
in its position as a growing commercial player within the framework of the European sport model
where non-profit and public sport providers still have a strong impact.
Methodology: We evaluate the financial performance of the Belgian fitness
industry using a time-trend analysis applying a cross-sectional research design for ...
in its position as a growing commercial player within the framework of the European sport model
where non-profit and public sport providers still have a strong impact.
Methodology: We evaluate the financial performance of the Belgian fitness
industry using a time-trend analysis applying a cross-sectional research design for ...