Projects
Institutional comparative research on active ageing: Multi-level analysis of the determinants of early retirement, reintegration an investment in employability. University of Antwerp
Study of the (patho)physiological role of NF-kB inhibitors A20 and ABINs through genetic Ghent University
The aim of the Odysseus project is to understand the function, activation and regulation of NF-kB activation and apoptosis by A20 and A20-interacting ABIN proteins, using conditional gene targeting in the mouse in combination with mouse models of human diseases. Such knowledge may lead to novel approaches to prevent and treat various inflammatory and degenerative disorders.
Chinese Discourse on Translation as Intercultural Communication ——Ulterior Agendas of the Chinese Literati in their Collaborative Translation with Jesuit Missionaries in Late Ming and Early Qing KU Leuven
From the end of the 16th century (Ming Dynasty, the Wanli Emperor) to the late 18th century (Qing Dynasty, the Qianlong Emperor), there was an approximately two-hundred-year prosperous China-Europe cultural communication. Such cultural exchange was partly characterized by the essential role of printing that produced a large number of translations of Western works into Chinese, mainly attributed to Jesuits, which were usually completed through ...
Successfulintroduction of the cultivation of sweet potatoes in Flanders PCG-Vegetable Research Centre
The role of kindlin-2 in adult skeletal muscle tissue and in its in vivo regeneration upon injury KU Leuven
Genetic mosaicism in the brain as a cause of Alzheimer’s Disease KU Leuven
The large majority of Alzheimer’s Disease (AD) is caused by a mix of genetic and environmental causes (mainly aging) and is called sporadic AD. A small group of AD is caused by single genetic mutations and is called familial AD. In this group of patients mutations are found in the genes that affect directly the generation of the typical lesions in the AD brain, i.e. amyloid plaques and tangles. The mutations are causative and explain the ...
Nephrogenesis in extremely low birthweight infants and nephropathogenesis in relation to biomarkers and research to long distance prognosis KU Leuven
The aims of this PhD–project were to a) determine screening criteria for HNF1B analysis in patients with congenital anomalies of kidney and urinary tract (CAKUT), b) generate an infrastructure to facilitate longitudinal follow–up of a birth cohort of former extremely low birth weight (ELBW) neonates and subsequent data pooling with other cohorts and c) to use this infrastructure to study the consequences of preterm birth and ...