The role of structural dynamics in protein function and evolvability. KU Leuven
During evolution 'peptides' are turned into 'proteins' by delegating the specific functions to such biopolymers in a sophisticated manner. Out of all available conformers, nature has to select a subset of them to allow each protein to recognize specific substrates. During the short evolutionary period, such functional specialization of a fix-length peptide can be faithfully explained by the protein evolvability theory. To rationalize the ...