Publications
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Evaluation of different cytomegalovirus (CMV) DNA PCR protocols for analysis of dried blood spots from consecutive cases of neonates with congenital CMV infections. Vrije Universiteit Brussel
Two protocols for the extraction of cytomegalovirus (CMV) DNA and two methods for
the amplification of CMV DNA in dried blood spots were evaluated for the
retrospective diagnosis of congenital CMV infection. During the period from 1996
to 2006, a urine screening program detected 76 congenitally infected neonates.
Stored Guthrie cards with blood from 55 cases and 12 controls were tested. Two
spots of dried blood ...
the amplification of CMV DNA in dried blood spots were evaluated for the
retrospective diagnosis of congenital CMV infection. During the period from 1996
to 2006, a urine screening program detected 76 congenitally infected neonates.
Stored Guthrie cards with blood from 55 cases and 12 controls were tested. Two
spots of dried blood ...
Surveillance of cytomegalovirus (CMV) DNAemia in pediatric allogeneic stem cell transplantation : incidence and outcome of CMV infection and disease Ghent University
Cytomegalovirus (CMV) remains a serious problem after hematopoietic stem cell transplantation (HSCT). To investigate the incidence of CMV infection and outcome we retrospectively analyzed 70 consecutive pediatric allogeneic HSCTs monitored by CMV polymerase chain reaction (PCR), with at least 1-year follow-up or until death. All patients at risk for CMV infection (CMV-seropositive patients and CMV-seronegative recipients transplanted from ...
Hearing configuration in children with cCMV infection and proposal of a flow chart for hearing evaluation Vrije Universiteit Brussel
OBJECTIVE:
This study had three main goals: (1) to determine the hearing configuration in hearing-impaired children born with a congenital CMV (cCMV) infection, (2) to see whether auditory neuropathy spectrum disorder (ANSD) was present, and (3) to propose a flow chart for the follow-up of hearing in children with cCMV.
DESIGN:
Hearing configuration and the presence of ANSD in cCMV infected children was ...
This study had three main goals: (1) to determine the hearing configuration in hearing-impaired children born with a congenital CMV (cCMV) infection, (2) to see whether auditory neuropathy spectrum disorder (ANSD) was present, and (3) to propose a flow chart for the follow-up of hearing in children with cCMV.
DESIGN:
Hearing configuration and the presence of ANSD in cCMV infected children was ...
Flemish cCMV registry: threshold variability Ghent University
Multiple phenotypic alterations caused by a c-type cytochrome maturation ccmC gene mutation in Pseudomonas aeruginosa Vrije Universiteit Brussel
In some Proteobacteria biogenesis of c-type cytochromes depends on the products of the ccmABCDEFG(H) genes, which encode inner-membrane proteins. Inactivation of some ccm genes, in particular ccmC, has an impact on other processes as well, including siderophore production and utilization. Non-polar insertions were generated in the Pseudomonas aeruginosa ccmA, ccmC, ccmE, ccmF and ccmH genes, and their impacts on different phenotypes were ...
Lack of CCM1 induces hypersprouting and impairs response to flow KU Leuven
Cerebral cavernous malformation (CCM) is a disease of vascular malformations known to be caused by mutations in one of three genes: CCM1, CCM2 or CCM3. Despite several studies, the mechanism of CCM lesion onset remains unclear. Using a Ccm1 knockout mouse model, we studied the morphogenesis of early lesion formation in the retina in order to provide insight into potential mechanisms. We demonstrate that lesions develop in a stereotypic location ...