Projects
Theoretical and experimental investigation of the effect of pressure on volumetric and mass flow rates in supercritical fluid chromatography, including the effects on axial dispersion and residence time Vrije Universiteit Brussel
Innovative preconcentrator modules for improved detection limits and increased separation performance in one- and multi-dimensional liquid chromatography Vrije Universiteit Brussel
Liquid Chromatography tandem Mass Spectrometry for Routine Measurement of Steroid Hormones in Human Serum KU Leuven
Steroid hormones are physiologically important molecules that are regularly measured in human serum to aid in the diagnosis or follow-up of a variety of conditions. Routine steroid hormone testing is currently often performed on completely automated platforms within clinical laboratories. The reaction principles behind these methods are invariably antibody-based. Although these assays are easy-to-use, some fundamental weaknesses remain such ...
Study and modeling of peak broadening in liquid chromatography columns packed with porous shell particles and development of alternative particle shapes. Vrije Universiteit Brussel
Development of spatial three-dimensional chromatography for the characterisation of complex proteome samples Vrije Universiteit Brussel
Trapped ion mobility quadrupole time of flight mass spectrometer hyphenated to automated high throughput liquid chromatography. University of Antwerp
Achiral and chiral targeted brain metabolomics in volume-limited samples: quest for broad coverage, sensitivity and throughput using chemical derivatization and miniaturized liquid chromatography tandem mass spectrometry. Vrije Universiteit Brussel
extracellular fluid and their role under physiological and
pathophysiological conditions, sensitive, selective and highthroughput LC-MS/MS methods that enable the quantification of a
broad range of neurochemicals are needed. Moreover, stereospecific
analysis of chiral amino and hydroxy acids is important as also the
minor enantiomers have been shown ...
SDS/EDTA-treated chromatography paper strips for laboratory confirmation of monkeypox virus in the context of the global mpox epidemiology KU Leuven
Monkeypox virus (MPXV) is the most important human orthopoxvirus which emerged after the global eradication of smallpox. It causes mpox, a disease characterized by a prodromal period followed by the typical maculo-papular rash. The disease was historically endemic in countries of Central and West Africa where we have observed an increasing trend in incidence for the past two decades. Importations of MPX occurred multiple times into USA, UK, ...
VORTEXLC : Vortex enhanced liquid chromatography for HbA1c monitoring based diabetes management in a globalized setting Vrije Universiteit Brussel
chronic complication of diabetes and appropriate follow up of the patients. The golden standard is an expert laboratory HPLC method
focusing on HbA1c quantification, which has limitations when other relevant hemoglobin variants are to be detected. For approximately
7 % of the world’s ...