Projects
Additive manufacturing of monolithic zirconia for dental restorations KU Leuven
Reinnervation and revascularization of dentin-pulp-like tissue in an in vivo model of pulp regeneration using a biodegradable scaffold and human dental pulp stem cells Hasselt University
Reinnervation of dentin-pulp-like tissue in an in vivo model of pulp regeneration using a biodegradable scaffold and human dental pulp stem cells. Hasselt University
Engineering biomimetic mechanically robust patient-specific CaP dental root scaffolds KU Leuven
The overall aim of this project is to develop a novel tissue engineering approach for dental root tissue replacement based on immune-modulation through biomaterial surface functionalization. In a first step, CaP scaffolds with a customized geometry and tailored mechanical properties will be fabricated by means of 3D printing. Currently available additive manufacturing (3D printing) technologies used to produce customized CaP structures ...
iDentgel: Immune-modulated dental pulp regeneration through dual-cure injectable nanocomposite hydrogel KU Leuven
Oral tissues are prone to infections and diseases that can lead to irreversible damage. Traditionally, oral tissue repair is established via restorative materials, replacing tooth and bony tissue. However, there is a tendency towards more natural procedures in regenerative dentistry by applying tissue engineering and regenerative medicine (TERM) techniques. TERM can be realized via cell-free and cell-based approaches, while dental tissue ...
Towards an improved dental pulp-capping therapy. KU Leuven
VITAL PULP THERAPY (pulp capping) is a clinical technique a dentist employs in an attempt to keep a traumatized tooth-pulp healthy, while avoiding an often technique-demanding and costly root-canal treatment that may weaken the tooth’s integrity and shorten its lifetime. Bioactivity towards the pulp-dentin complex is today considered a preferential property a modern dental restorative material should possess. The main pulp-capping agents ...
A multicenter randomized controlled study comparing connective tissue graft with collagen matrix to re-establish convexity at the buccal aspect of single dental implants Ghent University
Soft tissue augmentation procedures have been recommended to re-establish convexity at the buccal aspect of dental implants. Connective tissue graft is the gold standard but morbidity and patient discomfort have been described. Recently, a collagen matrix has been developed. The primary objective of this RCT is to compare both in terms of increase and stability of buccal soft
tissue profile.
Biological basis of Biomaterials – Dental Pulp tissue interaction KU Leuven
Maintaining pulp vitality has been identified as a major future role of tooth-restorative treatment, thereby emphasizing the importance/impact of this research project, in particular as the restoration of teeth accounts for the major part of everyday dental practice and nearly the whole population may need a tooth restoration sooner or later. The project aim is to contribute to a better understanding of biomaterial-pulp interactions and yet ...
Cariogenicity of composite tooth restorative materials KU Leuven
To restore carious or traumatized teeth, a dental practitioner can choose between two direct (plastic) restorative materials, namely amalgam (silver-colored) or composite (tooth-colored). It is obvious that the aesthetic properties of composites are important for patients, but composites also have the advantage of a minimally invasive preparation technique. Moreover, dental amalgams have been alleged of environmental pollution and even ...