Projects
The beta-cell and the immune system in type 1 diabetes: partners in crime - developing new therapies in type 1 diabetes through better understanding of beta-cell behaviour and use of novel immunomodulators. KU Leuven
Translational approaches to disease modifying therapy of type 1 diabetes: An innovative approach towards understanding and arresting Type 1 diabetes – time to harvest. KU Leuven
Prediction of pregnancy outcomes in women with gestational diabetes and their risk to develop diabetes postpartum. KU Leuven
Recently a one-step screening strategy with more stringent criteria to diagnose gestational diabetes (GDM) has been proposed by ‘The International Association of Diabetes and Pregnancy Study Groups’ (IADPSG). The use of this new screening strategy for GDM remains controversial, mainly because of paucity of data on the cost effectiveness of such strategy, the uncertainty on the clinical relevance of treatment of mild GDM based on the IADPSG ...
Early detection of Diabetes trough advanced data mining techniques. KU Leuven
Diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia, which may cause serious harm to many of the body's systems. Diabetes is a deadly pandemic which presents a significant burden on healthcare systems worldwide, and will continue to do so as its global prevalence rises rapidly (particularly type 2 diabetes). In developed countries, the rising prevalence is primarily driven by population aging, lifestyle changes ...
Promotion of a healthy lifestyle in women with a history of gestational diabetes KU Leuven
The prevalence of gestational diabetes (GDM) increases worldwide with rates between 9-35%, posing challenges to maintain high-quality care in the management of GDM. A valuable solution to cope with this increasing burden could be the organization of group education. In this research project, we will analyze the collected data of a prospective observational cohort study with the aim to evaluate women’s satisfaction about (group) education, ...
Neutrophils and post-translationally modified beta-cell proteins: a driving force behind type 1 diabetes? KU Leuven
Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by the selective destruction of the pancreatic insulin-producing beta cells by infiltrating immune cells, leading to an absolute insulin deficiency. The prevalence of T1D is increasing worldwide and the concern regarding the number of new T1D cases relates in part to the development of chronic complications, either microvascular (i.e., retinopathy, neuropathy, and ...
Link between residual beta cell function and glycemic variability in (pre)type 1 diabetes Vrije Universiteit Brussel
Relation between residual beta cell function and glycemic variability in (pre)type 1 diabetes. KU Leuven
Relation between residual beta cell function and glycemic variability in (pre) type 1 diabetes Ghent University
Type 1 diabetes develops when 60 to 90% of insulin-producing beta cellsahve been destroyed. This cell loss leads to greater variability of
blood glucose levels both before and after diagnosis. This variability is predictive of progression to clinical onset of diabetes in risk groups and of
frequenc of hypoglycemic events in patients. Novel beta cell therapy trials aim to prevent or cure diabetes by trying to preserve or restore ...