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The beta-cell and the immune system in type 1 diabetes: partners in crime - developing new therapies in type 1 diabetes through better understanding of beta-cell behaviour and use of novel immunomodulators. KU Leuven
Translational approaches to disease modifying therapy of type 1 diabetes: An innovative approach towards understanding and arresting Type 1 diabetes – time to harvest. KU Leuven
Boosting beta-cell function for treatment of type 1 diabetes KU Leuven
In type 1 diabetic (T1D) patients the pancreatic insulin-producing beta cells are selective destroyed by the immune system, leading to an impaired glucose metabolism. The steep increase in the incidence of this chronic autoimmune pathology especially in young children in the last decades raises serious concerns. To date, insulin therapy is considered the gold standard for the treatment of T1D. Nevertheless, limitations persist, such as the ...
The Belgian Diabetes in Pregnancy follow-up study (BEDIP FUS) KU Leuven
Closed-loop insulin delivery in pregnant women with type 1 diabetes (the CRISTAL study) KU Leuven
Type 1 diabetes (T1DM) during pregnancy is associated with increased risk of maternal and neonatal complications such as pre-eclampsia, preterm delivery, caesarean sections, congenital malformations and perinatal mortality. Even with increasing use of new continuous glucose monitoring (CGM) and continuous subcutaneous insulin infusion (CSII, insulin pumps) technologies, pregnant women with T1DM continue to spend on average 8 hours/day ...