Functional dissection of RNA modifiers in immune cells using CROPseq KU Leuven
The epitranscriptome – sum of chemical modifications of RNA –
comprises more than 170 RNA modifications, however, we only
begin to understand the function of a few. The most abundant RNA
modification is the isomerisation of uridine to pseudouridine (psi).
Despite its abundancy and despite the fact that mutated psi
synthases can cause human disorders, the regulated molecular
pathways and cellular consequences of ...