Projects

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High-resolution 7T fMRI imaging of object and category representations in the human brain KU Leuven

Hans Op de Beeck
Brain and Cognition

We plan to perform high-­resolution imaging, including a comparison of 3T and 7T results, in order to characterize category-selective VOTC regions in more detail: how many regions do we have for one particular category, and how do the functional regions relate to anatomy and cytoarchitecture? First initial steps have been taken to tackle these questions. We hope to replicate these findings and extend them to a wider range of categories, ...

Functional imaging (MRI) of starlings brains to unravel the neural basis of vocal communication in songbirds as a model for human communication. University of Antwerp

Colline Poirier
Bio-Imaging lab
Our project aims at understanding brain-behaviour interactions, with a special emphasis on the role of social factors on these interactions and as possible inducers of brain plasticity.This will be made possible by a whole brain approach, based on a rapidly expanding technique: small animal fMRI, applied to an original animal model: the European starling.

Data-driven microstructure imaging with multi-dimensional diffusion MRI in early brain development KU Leuven

Frederik Maes
Processing Speech and Images (PSI), King's College London (University of Lon

Understanding how human brain structure develops and grows before and around the time of birth is a grand challenge in neuroscience, with far reaching implications for our understanding of neuropsychiatric disorders. Diffusion MRI (dMRI) and other quantitative MRI relaxometry modalities offer a unique means to characterize neural tissue microstructure in vivo. However, analysis of multi-dimensional dMRI in neonatal and foetal data brings ...

Spherical deconvolution of high-dimensional diffusion MRI for improved microstructural imaging of the brain. University of Antwerp

Jan Sijbers
Vision lab
Multi-tissue spherical deconvolution of diffusion MRI (dMRI) is a popular analysis method that provides the full white matter fiber orientation density function as well as the densities of cerebrospinal fluid and grey matter tissue in the living human brain, completely noninvasively. It can be used to track the long-range connections of the brain and provides a tract-specific biomarker for neuronal loss in the study of neurodegenerative ...

Development of progressed estimating methods for the detection of brain activity with fMRI data. University of Antwerp

Jan Sijbers
Vision lab
The focus of this project is signal processing in functional MRI. Functional brain imaging offers a way to image the specific brain areas that are active during a specific action. Brain activation is present in the MRI images due to the BOLD (Blood Oxygen Level Depended) response. Since the BOLD response signal is weak compared to the noise level accurate modeling of the response as well as the disturbances will improve brain activation ...

Better magnetic resonance imaging of the brain through subject-specific 3D-printed shims KU Leuven

Rob Ameloot
Membrane Separations, Adsorption, Catalysis, and Spectroscopy for Sustainable Solutions (cMACS), Laboratory for Neuro- and Psychophysiology, Biomedical MRI
Magnetic resonance imaging (MRI) is a non-invasive medical imaging technique that is widely used to study anatomy and physiological processes, in both clinical practice and research. To obtain clear images, it is critically important that the applied magnetic field is as homogeneous as possible. Magnetic field inhomogeneities inherent to the scanning equipment can be corrected efficiently. However, the subject itself induces additional ...

Whole brain mesoscale functional imaging in macaques KU Leuven

Wim Vanduffel
Laboratory for Neuro- and Psychophysiology

The macaque monkey model is widely used for neuroscience studies, as it allows researchers to use invasive tools to systematically study the brain. In addition, the macaque brain is anatomically and physiologically more similar to the human brain than other animals used in research. However, due to the small size of the macaque brain, higher spatial resolution imaging is required to obtain the same level of structural detail in the macaque as ...

The aging brain in action: towards a multi-modal imaging approach of motor control. KU Leuven

Stephan Swinnen
Movement Control & Neuroplasticity Research Group

The aging population poses unprecedented challenges for society. Here, we will investigate age-related changes in the brain in relation to movement control. The basic premise is that age-related decreases in motor performance are associated with functional and structural changes in the brain. To achieve this goal, we will use a complementary multimodal imaging approach consisting of magnetic resonance imaging (MRI), electroencephalography ...

Can we use resting-state fMRI and CSD fiber tractography in presurgical mapping? KU Leuven

Stefan Sunaert
Translational MRI, Laboratory for Cognitive Neurology, Research Group Experimental Neurosurgery and Neuroanatomy

The brain is the most complex organ in the human body. It is a fascinating biological machine capable of processing massive amounts of information and performing a wide array of functions. In fact, it is so complex that we estimate that the number of connections between nerve cells (neurons) in the human brain to be about 100 times the number of stars in our neighboring Andromeda galaxy (1 trillion). However, like any other organ in our body, ...