Projects
Synaptic density, tau and multiparametric PET-MR for quantitative functional assessment and prognosis in acute and repetitive brain trauma, stroke and mild cognitive impairment KU Leuven
A neurosurgical approach to brain networks KU Leuven
Brain representations and predictions of social reactions in typical development and in people with autism KU Leuven
The human brain not only creates representations of the world (e.g., visual images on the retina) but also continuously makes predictions about the environment (e.g., what will I see next). One of the most complex tasks of the brain is to represent and predict social behavior of others. This social ability is impaired in individuals with autism spectrum disorders (ASD) but it is unclear at what level of the brain hierarchy this process is ...
How the interplay between basal forebrain neuronal populations determines brain state and how this is changed in Alzheimer's disease. University of Antwerp
How subjective value shapes sensory representations in the adult brain. KU Leuven
Compensatory neural recruitment as a result of traumatic brain injury: the penetration of cognition into action. KU Leuven
This project is about the fundamental study of changes in movement control and its coupling to executive functioning in children and young adults after sustaining a traumatic brain injury. Studying a complex motor tasks with high executive demands by means of functional magnetic resonance imaging (fMRI), we will expand the knowledge about changes in brain activity itself and its link to motor and cognitive behaviour. In addition, ...
Cognitive brain circuits and the spread of tau in vivo in humans KU Leuven
Alzheimer disease (AD) is pathologically defined by selective neuronal loss and decrease in synaptic density, the accumulation of fibrillar β amyloid plaques and intra- and extraneuronal deposition of phosphorylated tau as neurofibrillary tangles, neuropil threads and dystrophic neurites [6]. Dementia has been recognized as a global health care problem associated with significant economic and social burden. It is therefore important to get a ...
A neurosurgical approach to brain networks (FKM/16) KU Leuven
The goal of our research is an attempt to bridge the gap between clinical and basic neuroscience using intracranial recordings and fMRI in human patients and
compare these results with non-human primate studies. Combining electrophysiological recordings and functional imaging will allow us to gain more insights in widely applicable but indirect imaging methods. The goal of our current research is a detailed investigation of brain areas ...