Projects
Multimodal fluorescence microscopy and nanoscopy platform. KU Leuven
Fluorescence microscopy and super-resolution fluorescence microscopy -nanoscopy- offers the possibility to study in a non-invasive way structures ultimately down to the nanometer scale. The ability to do so dynamically will prove to be an indispensable tool in analyzing the molecular mechanisms and organization of living as well as non-living systems. Technological advances in the microscopy field have now resulted in commercially available ...
Advanced illumination techniques for high-contrast highresolution fluorescence and scattering microscopy Ghent University
In light microscopy an object is illuminated with a lamp or a laser and the transmitted,
reflected or fluorescent light is detected to get information on the object. In the project two approaches will be developed to study small particles and their interaction with living cells: Light Sheet Fluorescence Microscopy and Complex Beam Scattering Microscopy.
In standard fluorescence microscopy the entire sample is illuminated and there ...
High Resolution Structured Illumination Raster Scanning Fluorescence Microscopy KU Leuven
Fluorescence microscopy has become an indispensable tool in
biology and medicine. It is routinely used in drug development, to
diagnose health disorders and in DNA sequencing.
Despite enormous progress in instrumentation and deployment, high-
resolution microscopes remain expensive, bulky devices that require
skilled operators. As a consequence, they are found only in
specialized labs, limiting their ...
Development of advanced fluorescence microscopy methods for studying the structure, transport and stability of nanomedicines for gene therapy of the retinal pigment epithelium Hasselt University
FWO Hercules MZW: Light sheet fluorescence microscopy in life sciences and medical research Vrije Universiteit Brussel
Combined Scanning Electron and Super-Resolution Fluorescence Microscopy for dynamic studies in nanoscience and nanotechnology. KU Leuven
Visualisation of nanoscropic interactions in living systems using subdiffraction fluorescence microscopy KU Leuven
The proposed research aims to create a framework for the visualization of nanoscopic structures and interactions in complex systems, such as living cells and tissues, using diffraction-unlimited fluorescence microscopy. The project builds on a technique developed by the applicant, photochromic stochastic optical fluctuation imaging (pcSOFI), which uses genetically encoded labels and is considerably more robust and more widely applicable than ...
Combining fluorescence microscopy and microfluidic devices as an innovative in-situ characterization technique for thin-film (nano)composite membranes KU Leuven
Interfacially polymerized (IP) polyamide (PA) thin-film composite membranes (TFC) are dominant in desalination, wastewater treatment and other industrial separation processes thanks to their high water fluxes and unrivaled salt rejection. However, these membranes suffer a trade-off between permeance and selectivity. A promising strategy to overcome this trade-off is by incorporating fillers into the selective top-layer of TFC membranes to ...