High-resolution manometry evaluation of the role of colonic dysmotility in symptom generation and therapeutic outcomes in functional bowel disorders. KU Leuven
Colonic function is impaired in functional bowel disorders (FBDs), which are characterized by disordered bowel movements (diarrhoea, constipation), pain, discomfort of bloating. The most
important FBDs are functional constipation, chronic diarrhea and the irritable bowel syndrome. We hypothesize that contractions of the colon and their control are disturbed in FBDs, and that this explains their symptoms both in terms of disordered bowel ...