Decrypting deficient embryo-endometrium interaction in infertility using cutting-edge blastocyst and endometrium models: spotlights on endometriosis and polycystic ovary syndrome KU Leuven
One week after fertilization, the human embryo implants into the uterus, requiring highly coordinated crosstalk with the uterine lining (endometrium). To welcome and nest the nascent embryo (blastocyst), the endometrium must decidualize and reach a receptive state. Perturbed decidualization and receptivity are considered to be major causes of infertility. Here, we will deeply decrypt aberrations in these processes in two widespread burdening ...