Sustained release of lactic acid from an intravaginal device Ghent University
We seek funding to optimize and clinically validate a lactic acid‐eluting system to combat and prevent recurrent bacterial vaginosis in humans. Under physiological conditions, the vagina harbors a commensal microflora primarily consisting of lactic acid‐producing lactobacilli, thus creating an acidic environment (pH 3.5‐4.5) which provides natural antimicrobial protection to the lower female genital tract. However, during bacterial vaginosis ...