Determination of subunit composition and architecture of supramolecular and biological complexes using mass spectrometry coupled with ion mobility spectroscopy and allied techniques. University of Antwerp
We are developing and applying new methods for the intact characterisation of supramolecular systems, particularly noncovalent complexes of biomolecules (proteins, DNA/RNA and ligands), based on soft ionisation techniques such as electrospray ionisation and laser desorption methods, coupled with mass spectrometry and ion mobility spectroscopy. Extensive collaboration with colleagues in the areas of Biochemistry and Chemistry are envisaged.