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BACKGROUND: The inability to rapidly detect SARS-CoV-2 infection during the COVID-19 pandemic inspired strict lockdown policies, resulting in unprecedented economic adversity and clogging the health care sys-tem. As countries’ fears for second and third wave outbreaks are becoming reality, there is an urgent need for globally available, easy-to-perform, non-invasive, on-the-spot diagnostic tests to detect SARS-CoV-2 and to predict COVID-19 ...
Early and appropriate antibiotic therapy are crucial determinants for successful treatment of severe bacterial infections. Suboptimal antibiotic exposure has been shown to lead to worse clinical outcome (e.g., prolonged antibiotic course, prolonged length of stay, increased mortality). Hence, antibiotic exposure should be high enough to maximize the likelihood of clinical success, but not too high to avoid unnecessary toxicity. Beta-lactams ...
This interdisciplinary coordinated research action aims at elucidating geneenvironment interactions in three highly prevalent smoking-induced lung diseases with important morbidity, disability and mortality: asthma, chronic obstructive pulmonary disease COPD) and lung cancer. Ultimately, the aim is to elucidate pathogenetic pathways and networks, to identify new targets and to develop new drugs to alleviate these common respiratory ...
In a greying society, the possible benefits from physical activity [PA] regarding independence and different aspects of health are frequently emphasized. Furthermore, recent research shows a strong association between healthy ageing and a physically active lifestyle, even when adopted at a later age (Hamer, Lavoie, & Bacon, 2013). Within the Physical Activity, Sports & Health research group, in previous ...