A multimodal non-linear optical platform for 2l3-photon excitation and 2ndl3rd harmonic imaging deep inside living tissues and animals (Multimodal NLO imaging platform) Ghent University
The infrastructure is an advanced and multimodal non-linear optical (NLO) imaging platform for imaging of cells in their native, intact, 3-dimensional (3D) environment over extended periods of time using 2-photon (2P) and 3-photon (3P) excitation principles while providing extra structural context and label-free information by exploiting 2nd and 3rd harmonic signals generated by endogenous molecules, nanomedicines or pollutants.
The platform with its dual 2P|3P pulsed laser configuration:
* allows to reach deeper into tissue structures, enabling non-invasive in-vivo optical ...