Promising theranostic hybrid systems based on Inorganic Nanoparticles coated with Poly(2-oxazoline)s-conjugates for combination cancer therapy Ghent University
Combination therapies can address the intractability of cancer and provide a better and promising approach for tumor therapy compared to single-mode therapy. The focus of the current project is the development of the chemical approaches to prepare the Doxorubicin-Poly(2-alkyl-2-oxazoline)s conjugates with a cathepsin cleavable valine-alanine dipeptide linker and proper end-group modification to attaching onto Au NPs and (iron oxide ...