Projects
A high-resolution and high-sensitivity hybrid small animal PET-CT system for combined molecular/functional and anatomical preclinical imaging in neurology, oncology and cardiology. KU Leuven
Molecular imaging allows non-invasive in vivo visualization, characterization and quantification of biological and pathophysiological processes that can be longitudinally monitored in specific (transgenic) animal models of human diseases in a physiological environment. The hybrid small animal PET-CT system will provide molecular information with high sensitivity and submillimeter resolution co-registered with anatomical information within one ...
Evaluation of p53 aggregation as a drug target in oncology. KU Leuven
The aim is to demonstrate the clinical relevance and the diagnostic / therapeutic value of p53 aggregation.
Analysis of policies regarding market access of oncology drugs. KU Leuven
Changing demographics, earlier detection and treatment of cancer and a growing number of therapeutic options and combination therapies lead to an increasing trend in expenditures on cancer medicines. Regulations for market access of cancer medicines, including marketing authorization, price setting and reimbursement, should ensure that effective and safe medicines are affordable for society, accessible for individual patients and profitable ...
An oncology centre at the University of Health Sciences on Phnom Penh: a challenge forexpanding teaching and research facilities Ghent University
Development objective: improvement of public health care. The Cambodian society will benefit from an anticancer programme. This programme leads to the improvement of public health in general.
Academic objective: introduction of a scientifically based cancer treatment strategy by echeloning a cancer prevention and therapy programme at the UHS and affiliated university hospitals.
The implementation of an oncology nursing clinic for patients with breast cancer Ghent University
The implementation of an oncology nursing clinic for patients with breast cancer - Conducting a literature review related to the information needs of patients with breast cancer. - Helping analyzing the focus group interviews with breast nurses - Performing and analyzing in-depth interviews with breast nurses - writing a script for breast nurses in organizing an oncology nurse consultation - To implement and analyze in-depth interviews with ...
Optimizing the conduct and implementation of patient preference research in drug development and evaluation: a focus on oncology and COVID-19 KU Leuven
Patient preferences and patients' views are increasingly seen as an important source of information that should be taken into account when making decisions throughout the whole drug life cycle. However, decision-making is now predominantly done by non-patient stakeholders (such as the industry, regulatory agencies and clinicians). Moreover, patients' needs and preferences are not always in line with those of the other stakeholders. As a ...
Quality improvement of diagnostic processes in the oncology field KU Leuven
15 to 20% of the breast cancer patients have an excessive presence of the Human Epidermal growth factor Receptor 2 (HER2) protein. The determination of the HER2 status of breast cancer patients is therefore used during the diagnosis and further therapy determination. ASCO guidelines are available for this assessment. Because the regulation regarding the reimbursement of this test allowed to not apply the most recent guideline, the proposed ...
Tenure track professorship in pediatric precision oncology Ghent University
A tenure track appointment grants one the privilege of focusing primarily on research for a period of 5 years, with a limited teaching load.
Single-cell omics data analysis in translational oncology KU Leuven
Cancer consists of (epi)genetically and phenotypically different populations of single cells. This intra-tumor cellular heterogeneity underlies therapeutic resistance to cancer treatment. Thus, deciphering intra-tumor cellular heterogeneity, both in cancer cells and their surrounding stromal cells down to the single-cell resolution is essential to combat therapeutic resistance and to develop more effective cancer drugs. The state-of-art ...