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Patient and treatment characteristics associated with patient activation in patients undergoing hemodialysis: a cross-sectional study KU Leuven

BACKGROUND: Patient activation is associated with better outcomes and lower costs. Although the concept is widely investigated, little attention was given to patient activation and its predictors in patients undergoing hemodialysis. Hence, we aimed to investigate the level of patient activation and aimed to determine patient- and treatment-related predictors of activation in patients undergoing hemodialysis. METHODS: This cross-sectional ...

Europa Uomo Patient Reported Outcome Study (EUPROMS) Descriptive Statistics of a Prostate Cancer Survey from Patients for Patients KU Leuven

Hendrik Van Poppel

BACKGROUND: Europa Uomo initiated the Europa Uomo Patient Reported Outcome Study (EUPROMS) to collect prostate cancer (PCa) patient-reported outcome (PRO) data as a primary endpoint. OBJECTIVE: To inform future PCa patients about the impact of PCa treatment through self-reported PRO data of fellow patients collected outside a clinical trial setting. DESIGN, SETTING, AND PARTICIPANTS: A cross-sectional survey was conducted among PCa patients ...

A Retrospective Analysis of Dabrafenib and/or Dabrafenib Plus Trametinib Combination in Patients with Metastatic Melanoma to Characterize Patients with Long-Term Benefit in the Individual Patient Program (DESCRIBE III) Vrije Universiteit Brussel

Massimo Aglietta, Paolo A Ascierto, Ana Arance, Bart Neyns

The dabrafenib plus trametinib (dab + tram) combination has demonstrated durable long-term efficacy in patients with BRAF V600-mutant metastatic melanoma. However, real-world data characterizing patients with long-term benefit are limited. DESCRIBE III was a global, observational, retrospective, chart review study in patients with unresectable or metastatic melanoma treated with dab monotherapy and/or dab + tram combination therapy as part of ...

Do self-management interventions in COPD patients work and which patients benefit most? An individual patient data meta-analysis KU Leuven

Thierry Troosters

Self-management interventions are considered effective in patients with COPD, but trials have shown inconsistent results and it is unknown which patients benefit most. This study aimed to summarize the evidence on effectiveness of self-management interventions and identify subgroups of COPD patients who benefit most.

Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? : an observation from the Defining Antibiotic Levels in Intensive care unit patients ( Ghent University

Mohd H Abdul-Aziz, Jeffrey Lipman, Murat Akova, Matteo Bassetti, Jan De Waele, George Dimopoulos, Joel Dulhunty, Kirsi-Maija Kaukonen, Despoina Koulenti, Claude Martin, et al.

Measurement Properties of Patient Health Questionnaire 9 and Patient Health Questionnaire 2 in Adult Patients With Atopic Dermatitis Vrije Universiteit Brussel

Brad Lee, Muhammad Yousaf, Sherief Janmohamed, Rajeev Chavda, Sylvie Gabriel, Kevin R Patel

BACKGROUND: Few outcome measures were validated for assessing depressive symptoms in AD. Patient Health Questionnaire-9 (PHQ9) and the abridged PHQ2 are established patient-reported outcome measures of depressive symptoms.

OBJECTIVE: We sought to examine the measurement properties of PHQ9 and PHQ2 in adult AD. A prospective dermatology-practice based study of 458 AD patients (age 18-97 years) was conducted.

RESULTS: PHQ9 strongly ...

Health Care Communication Technology and Its Promise of Patient Empowerment: Unpacking Patient Empowerment Through Patients’ Identity Constructions Hasselt University

Laura VISSER, Inge Bleijenbergh, Yvonne Benschop, Allard VAN RIEL

Epidemiology and outcome of nosocomial bloodstream infection in elderly critically ill patients: a comparison between middle-aged, old, and very old patients Ghent University

Stijn Blot, Mustafa Cankurtaran, Mirko Petrovic, Dominique Vandijck, CHRISTELLE LIZY, Johan Decruyenaere, CHRISTIAN DANNEELS, Koenraad Vandewoude, Anne Piette, Gerda Verschraegen, et al.

Background: We investigated the epidemiology of nosocomial bloodstream infection in elderly intensive care unit (ICU) patients. Methods: In a single-center, historical cohort study (19922006), we compared middle-aged (45-64 years; n = 524), old (65-74 years; n = 326), and very old ICU patients (>= 75 years; n = 134) who developed a nosocomial bloodstream infection during their ICU stay. Results: Although the total number of ICU admissions ...

Scalp cooling in breast cancer patients treated with docetaxel–cyclophosphamide: patient‑ and nurse‑reported results KU Leuven

Annemarie Coolbrandt, Patrick Neven, Kevin Punie, Hans Wildiers

PURPOSE: Recent evidence supports the efficacy of scalp cooling in preventing chemotherapy-induced alopecia in breast cancer treatments. However, efficacy largely varies between treatment regimens. The aim of this study was to explore the patient- and nurse-reported results of scalp cooling in terms of hair loss and need for a wig/head cover in patients with breast cancer treated with 3-weekly docetaxel 75 mg/m2- cyclophosphamide 600 mg/m2. ...

Patient- and physician-level determinants of blood pressure response to treatment in normal weight and overweight patients (the PREVIEW study) Vrije Universiteit Brussel

I Abraham, Karen Macdonald, M. Song, G Ciesielski, C Pacheco, C Lee, M Cholette, K Kinsey, P Speaks, C. Hermans, et al.

Background and aims: Obesity combined with hypertension places patients at greater risk for target-organ damage and cardiovascular disease. The purpose of this secondary analysis was to identify physician-and patient-levels determinants of blood pressure (BP) values and predictors of uncontrolled BP through subgroup analysis by body mass index (BMI).

Methods and results: We conducted a subgroup analysis of 3006 patients with ...

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