Projects
Providing sitting balance training with a newly developed rehabilitation device in the chronic stage after stroke: a pilot randomized controlled trial KU Leuven
Adequate sitting balance is a key determinant of motor and functional recovery after stroke; patients with better sitting balance ability early after stroke have a higher chance of better motor and functional status at six months. Thus, an important part of rehabilitation is focused on training sitting balance. What is currently unavailable is a rehabilitation device that allows patients to train sitting balance independently as this would ...
A pilot study of the OptiMEDs intervention: A complex intervention for multidisciplinary review (including nurses, pharmacists, and physicians) in nursing homes, with ICT-support for the evaluation of the appropriateness of prescribing and for side-effect Ghent University
The interest in improving the pharmacotherapy of older adults in nursing homes is growing. We propose a method intending to support the decision of GPs regarding the pharmacotherapy of older adults. To achieve this, we introduce the OptiMEDs intervention: a combination of an electronic decision support tool (for the appraisal of potentially inappropriate medication use, anticholinergic use, or medications that can be de-prescribed in view of ...
Understanding and improving well-being of frail older people with cancer: longitudinal study and randomised controlled trial Vrije Universiteit Brussel
However, many do not receive palliative care, or only shortly before death. First, to better understand the complex needs ...
Subcontracting Bill & Melinda Gates: Design of the STH pilot study: Evaluate cfDNA as a biomarker of STH infection Ghent University
The gastrointestinal tract of a child living in a low income country is highly likely to be parasitized with at least one of three main Soil- transmitted helminths (STH; Ascaris /umbricoides (roundworms), Trichuris trichiura (whipworms), Ancylostoma duodenale and Necator americanus (hookworms). Ascaris a·nd Trichuris are the most prevalent infecting 800-1100 million people and 600-800 million people respectively. The disease burden ...
Pilot study: development of a multidisciplinary return-to-work intervention for employees with burnout KU Leuven
About one out of three Belgian employees on sick leave for more than one year has been diagnosed with a psychological disorder. Among these employees, people suffering from burnout are more frequently and longer on sick leave compared to others. The aim of this project is to develop and assess the effectiveness of a return-to-work intervention that prevents long-term sick leave and permanent work disability due to burnout. This intervention ...
Impact of an intensive rehabilitation programme integrating advanced rehabilitation technology for adults in the chronic phase after a stroke: A randomised controlled trial. KU Leuven
The doctoral research consists of a four-year project. The overall aim of this project is to gain knowledge about the effectiveness of an intensive rehabilitation programme using advanced technology in adults with neurological disorders in the chronic phase. This project consists of data collection and analysis of a pilot study (1) and a large phase III randomised controlled trial (2).
(1) The pilot study was conducted in 2022 and had ...
The effect of extended heart failure Audit and Feedback on cardiovascular hospitalizations in general practice: a randomized controlled trial KU Leuven
RECOVER@HOME - Recovery from disability after geriatric home-rehabilitation versus standard of care: a randomised, multicentre, parallel group pragmatic trial in older patients with disability at hospital discharge. KU Leuven
Older patients who are hospitalised often experience disability, meaning dependence in activities of daily living such as washing, bathing, mobility, or shopping. Yet once discharged, most patients do not receive the follow-up care. As a result, patients need more assistance of informal and formal caregivers, they experience a lower quality of life, and have a higher risk for hospital readmission and nursing home admission.
Effective ...
The time course of impaired glutamate transmission, neuroinflammation, glucose metabolism and structural changes in human Amyotrophic Lateral Sclerosis: an integrated multimodal PET/MR study KU Leuven
ALS is a neurodegenerative disease with progressive muscle loss and an average survival of 2 to 5 years after symptom onset. Until now, no curative treatment is available. The general aim of this PhD was to investigate a triad of interrelated in-vivo imaging biomarkers that may be used for diagnosis and prognosis and the study of their physiopathological significance in ALS: glucose metabolism, neuroinflammation and synaptic ...