Development of a biorelevant in vitro drug release method for long-acting injectable nanosuspensions of poorly soluble drugs. KU Leuven
Sustained parenteral drug delivery can significantly improve treatment adherence and, hence, the clinical outcome of various chronic illnesses, such as HIV and schizophrenia to name just a few. Long-acting injectable (LAI) nano-/microsuspensions constitute an attractive formulation strategy for poorly soluble drugs and have been the subject of increasing research (Chapter 1). These LAI formulations possess unique features offering ...