Development of a self-emulsifying solid dosage form via co-processing of polyglycolised glyceride/polymer-mixtures with pharmaceutical carriers: enhancement of the bioavailability of poorly water soluble drugs Ghent University
The first aim of this project is to evaluate the potential of polyglycolised glyceride/polymer-mixtures for improving the solubility and bioavailability of itraconazole (used as a model for poorly water soluble drugs). The second aim of this project is to co-process the drug/SEDDS-mixture with a carrier in order to obtain a product (powder, granules) suitable for compression.