18F-PSMA-1007 PET/MR imaging, quantification and radiomics in the primary staging of prostate cancer and response prediction after neoadjuvant hormonal therapy KU Leuven
Prostate-specific membrane antigen (PSMA) is a cell-surface glycoprotein overexpressed on prostate cancer (PCa) cells. At present, PSMA PET is the gold standard to localize disease in patients with biochemically recurrent PCa and guides treatment in this clinical scenario. However, the role of PSMA PET in primary staging and its effect on patient management and outcome has only been studied in a limited number of mostly retrospective studies. ...