Projects
Biocompatibility of resin-based dental materials: Relating exposure to cell responses KU Leuven
Every year, resin-based dental restorative materials are used as the standard material in hundreds of millions of patients to restore tooth tissue lost due to trauma or caries. With their increased use, concerns about their potential health risks have been raised. Even though adverse effects induced by dental materials are believed to be infrequent and mild, many individuals potentially may be affected considering the number of patients ...
Release of Bisphenol A and other endocrine-disruptive compounds from resin-based dental materials KU Leuven
Whereas amalgam was previously the standard dental restorative material for carious or traumatized teeth, dental composites are nowadays routinely used. Their application is even expected to increase since the WHO has started propagating a general phasing down of the use of amalgam. After a widespread clinical use of more than 25 years, dental composites appear an acceptable biological and functional substitute for amalgam. Yet, their ...
Biocompatibility and cariogenicity of resin-based dental materials. KU Leuven
To restore carious or traumatized teeth, a dentist can choose between two direct (plastic) restorative materials, i.e. amalgam (silver-colored) or composite (tooth-colored). To restrict environmental mercury pollution, the WHO (World Health Organization) currently encourages a global phasingdown of the use of dental amalgam. Tooth tissue lost due to trauma or caries is nowadays preferentially replaced with composite. After a widespread ...
Intra-oral degradation of resin-based dental materials KU Leuven
Resin-based dental materials are used in all disciplines in dentistry, and have many advantages. Beside their esthetic properties (tooth-colored), they can be glued to remaining tooth tissue. This tooth-sparing approach is much less invasive than previous (metal) restorations, and it is generally recognized that this will aid in maintaining teeth as long as possible in good conditions. Unfortunately, resin-based materials undergo degradation ...
Biocompatibility and cariogenicity of resin-based dental materials. KU Leuven
Safe bioaromatic diols for sustainable resin-based dental materials KU Leuven
Biocompatibility and cariogenicity of resin−based dental materials KU Leuven
The proposed research program encompasses a new research line within the BIOMAT Research Cluster that combines both material sciences and biological expertise. With this translational research project, we want to explore several yet unknown properties of resin−based restorations (so−called 'composite fillings'). The final aim of this multi−disciplinary research is to contribute to the development of future dental restorative materials ...
Biocompatibility and cariogenicity of composite dental restorative materials. KU Leuven
Towards an improved dental pulp-capping therapy KU Leuven
SUMMARY.
A recent Delphi survey on the future of restorative dentistry for the next 20 years identified maintenance of the pulp vitality as of the highest importance [1]. The authors rated bioactivity toward the pulp-dentin complex as key property for future tooth-restorative materials. This need to develop bioactive restorative materials was also the conclusion drawn on a workshop ("Future innovation and research in dental restorative ...