Projects
The effect of conservative treatment of temporomandibular disorders on somatic tinnitus. University of Antwerp
The effect of conservative treatment of temporomandibular disorders on somatic tinnitus. University of Antwerp
Somatic ribosome defects as target for cancer therapy KU Leuven
Mutations in different ribosomal proteins have been described in a series of inherited disorders, known as ribosomopathies. These syndromes come with a variety of symptoms, including hematopoietic defects and a predisposition to develop leukemia and solid tumors later in life. This transition from hypo- to hyperproliferation is a long-standing paradox in the field and the underlying mechanisms by which such ribosomal protein mutations promote ...
Modal collocation and how delicate modal systems can be. A cognitive-functional corpus study of semantic and syntactic effects of collocation between modal verbs and modal adverbs in UK and US English. University of Antwerp
Influence of nuclear quantum effects on the static and dynamic properties of protic molecules in nanoporous materials Ghent University
Nanoporous materials, including zeolites and metal-organic frameworks (MOFs), make up a class
of materials characterized by exceptional chemical and physical properties. Their use in various
applications ranging from catalysis and selective adsorption to gas storage or separation –or the
promise they hold within that matter, drives the necessity of a thorough understanding of their
properties at ...
Modeling of non-linear effects in the design of reinforced concrete structures with static linear finite element Ghent University
The project aims to achieve a reasoned calculation of non-linear and time-dependent effects in the design of reinforced concrete structures. The mathematical model is developed with a view to the implementation of accounting software based on finite linear static (rod or plate) elements. The mathematical model allows to model non-linear effects via stepwise variable stiffness.
Somatic mutations explain missing risk of multiple sclerosis. KU Leuven
Somatic mutations explain missing risk in multiple sclerosis
An Goris, Laboratory for Neuroimmunology, KU Leuven
1. State of the art
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, affecting 2.5 million
people worldwide and leading to important physical and cognitive disability with typical onset during
young adulthood. A genetic component has long been demonstrated and through ...
PhD in collaborative care for the elderly with psychological and somatic frailty KU Leuven
More than two-thirds of older patients receiving psychiatric care have at least one general medical condition, and many of these patients have at least two. Management of multimorbidity requires integration of somatic and mental health care. Collaborative care is a complex intervention based on management models for chronic conditions and consists of four key elements: a multi-professional approach to care, a structured care plan, planned ...
Detection of somatic mutations and disease-defining methylation patterns in brain tissue and cerebrospinal fluid of patients with non-acquired focal epilepsy Ghent University
The majority of non-acquired focal epilepsies (NAFE) have a presumed genetic etiology. However, the current yield of diagnostic genetic testing in affected patients is very low. This diagnostic gap is an important barrier to the broader use of gene-targeted therapies. Increasing evidence from resected brain tissue of individuals with NAFE points towards an important role of pathogenic somatic variants and methylation abnormalities. Most NAFE ...