Use of optimized pluripotent stem cell derived hepatocytes for evaluation of the biology of viral replication of hepatitis viruses. KU Leuven
Worldwide more than 570 million people are chronically infected by the hepatitis B (HBV) or the hepatitis C virus (HCV) which often leads to cirrhosis and hepatocellular carcinoma. In addition, the hepatitis E virus(HEV) is a potential threat due to the increasing zoonotic transmissionwhich highlights the need for anti-HEV drug development and prevention in the near future. Unfortunately, research of these viruses is hamperedby the lack of ...