Publications
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Adverse reactions to tocolytics: Atosiban v nifedipine University of Antwerp
Different effects of tocolytic medication on blood pressure and blood pressure amplification Ghent University
The combination of corticosteroid and tocolytic therapy in a preeclamptic patient is a risk factor for the development of acute pulmonary oedema Hasselt University KU Leuven
Use of antenatal corticosteroids and tocolytic drugs in preterm births in 29 countries: an analysis of the WHO Multicountry Survey on Maternal and Newborn Health Ghent University
Background: Despite the global burden of morbidity and mortality associated with preterm birth, little evidence is available for use of antenatal corticosteroids and tocolytic drugs in preterm births in low-income and middle-income countries. We analysed data from the WHO Multicountry Survey on Maternal and Newborn Health (WHOMCS) to assess coverage for these interventions in preterm deliveries. Methods: WHOMCS is a facility-based, ...
Tocolytic indomethacin: effects on neonatal haemodynamics and cerebral autoregulation in the preterm newborn KU Leuven
BACKGROUND: Indomethacin has vasoactive properties in cerebral and systemic vascular beds, and it improves cerebral autoregulatory ability. We speculated that tocolytic indomethacin will improve cerebral autoregulatory ability in the very preterm infant in early postnatal life. METHODS: Eighteen stable preterm infants gestational age (GA) 25.3-29.6 weeks, birth weight (BW) 660-1430 grams), whose mothers had received 50-150 mg of tocolytic ...
Adverse drug reactions to tocolytic treatment for preterm labour: prospective cohort study KU Leuven
OBJECTIVE: To evaluate the incidence of serious maternal complications after the use of various tocolytic drugs for the treatment of preterm labour in routine clinical situations. DESIGN: Prospective cohort study. SETTING: 28 hospitals in the Netherlands and Belgium. PARTICIPANTS: 1920 consecutive women treated with tocolytics for threatened preterm labour. MAIN OUTCOME MEASURES: Maternal adverse events (those suspected of being causally related ...
Tocolytic therapy: a meta-analysis and decision analysis University of Antwerp
Anaesthesiological considerations on tocolytic and uterotonic therapy in obstetrics University of Antwerp
Aim: Significant side effects of tocolytic and uterotonic substances may be of concern to the anaesthesiologist. Recently, new drugs have been introduced having less side effects for both the mother and the neonate. Methods: A literature search was undertaken mainly focusing on meta-analyses, to review the possible side effects that might affect the course of anaesthesia and to suggest which precautions should be considered to prevent the ...