Projects
Development of Salmonella live attenuated vaccine strains for various serotypes in layers+ broilers Ghent University
Vaccines have been produced but most of the current vaccines are undefined mutants produced by chemical mutagenesis or by isolating ‘atural’mutants of wild-type strains. The current project aims to A) produce a combined Salmonella Enteritidis/Typhimurium vaccine that protects against shedding and colonization by strains of both serotypes in broilers, and B) a Salmonella Gallinarum vaccine that protects against fowl typhoid in layers. ...
Vaccine hesitancy in the (post-) COVID-19 EU: Effects of European identity, party orientation, trust and political polarization. University of Antwerp
MIRACLE: autonomous microfluidic patch for plasmid-based vaccine KU Leuven
Vaccine and diagnostics development against swine dysentery Ghent University
An efficient vaccine would be a useful weapon in the fight against dysentery in pigs. Our research group used an avirulent strain of B. hyodysenteriae in an in vivo vaccination trial. The use of this strain as a weakened live vaccine seems promising. In a first phase, further research would mainly focus on confirming the efficacy and safety of the vaccine strain in a large vaccination experiment. The vaccine strain would be tested in a model ...
A novel, DNA-based, live-attenuated vaccine for the yellow fever virus and other medically important flaviviruses. KU Leuven
Many vaccines are still composed of a purified antigen or a whole, inactivated pathogen combined with adjuvants. Alternatively, as is the case for yellow fever virus (YFV), measles, mumps and rubella, purified, live-attenuated virus vaccines are available. Both types of vaccines are expensive to produce and require a cold distribution chain from manufacturer to patient, which is in particular hard to achieve in resource-poor or remote ...