Serine auxotrophy: a novel metabolic vulnerability of platinum resistant ovarian cancers? KU Leuven
Ovarian cancer is the eight most common type of cancer in women and accounts for the second highest number of gynecological cancers associated deaths in the developed world. While for many cancer types the overall survival increased over the last years, this is unfortunately not true for ovarian cancer, showing a stagnation over the last decades. For over 40 years standard of care consists out of platinum-based chemotherapy, with or without ...