Onderzoeker
Aleksandra Siekierska
- Disciplines:Microbiologie, Systeembiologie, Laboratoriumgeneeskunde
Affiliaties
- Laboratorium Virologie en Chemotherapie (Rega Instituut) (Afdeling)
Lid
Vanaf14 mrt 2022 → Heden - Moleculaire Bio-ontdekking (Afdeling)
Lid
Vanaf1 apr 2013 → 13 mrt 2022
Projecten
1 - 1 of 1
- In vivo modellering in zebravis van epileptische encephalopathieën veroorzaakt door mutaties in aminoacyl-tRNA synthetasen.Vanaf1 okt 2015 → 30 sep 2018Financiering: FWO mandaten
Publicaties
1 - 10 van 22
- Modulation of sleep behavior in zebrafish larvae by pharmacological targeting of the orexin receptor(2022)
Auteurs: Aleksandra Siekierska, Peter de Witte, Daniëlle Copmans
- Hyperactivation of mTORC1 in a double hit mutant zebrafish model of tuberous sclerosis complex causes increased seizure susceptibility and neurodevelopmental abnormalities(2022)
Auteurs: Ann-Sofie De Meulemeester, Lise Heylen, Aleksandra Siekierska, Peter de Witte
- Connectivity Mapping Using a Novel sv2a Loss-of-Function Zebrafish Epilepsy Model as a Powerful Strategy for Anti-epileptic Drug Discovery(2022)
Auteurs: Lise Heylen, Michèle Partoens, Peter de Witte, Aleksandra Siekierska
- Ethylenediamine derivatives efficiently react with oxidized RNA 3′ ends providing access to mono and dually labelled RNA probes for enzymatic assays and in vivo translation(2022)
Auteurs: Aleksandra Siekierska, Peter de Witte
- Pericardial Injection of Kainic Acid Induces a Chronic Epileptic State in Larval Zebrafish(2021)
Auteurs: Lise Heylen, Ann-Sofie De Meulemeester, Daniëlle Copmans, Youcef Kazwiny, Pieter Vanden Berghe, Peter de Witte, Aleksandra Siekierska
- Modeling Neurodevelopmental Disorders and Epilepsy Caused by Loss of Function of kif2a in Zebrafish(2021)
Auteurs: Michèle Partoens, Ann-Sofie De Meulemeester, Peter de Witte, Aleksandra Siekierska
- G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling(2021)
Auteurs: Ann-Sofie De Meulemeester, Aleksandra Siekierska, Peter de Witte
Pagina's: 655 - + - Defining the phenotype of FHF1 developmental and epileptic encephalopathy(2020)
Auteurs: Aleksandra Siekierska, Lieven Lagae, Gunnar Buyse
Pagina's: E71 - E78 - Biallelic VARS variants cause developmental encephalopathy with microcephaly that is recapitulated in vars knockout zebrafish(2019)
Auteurs: Aleksandra Siekierska, Michèle Partoens, Jo Sourbron, Peter de Witte
- Non-canonical mTOR-Independent Role of DEPDC5 in Regulating GABAergic Network Development(2018)
Auteurs: Aleksandra Siekierska, Peter de Witte
Pagina's: 1924 - +
Patenten
1 - 2 van 2